Artificial Ovaries Bring New Hopes For Young Cancer Patients

Artificial Ovaries Bring New Hopes For Young Cancer Patients

But there is a small risk that in those with cancer the ovarian tissue may contain cancerous cells, raising the chances of the illness returning when the transplant takes place. That's for a number of reasons (including the obvious reality that mice are very different mammals with different biologies from human beings); for instance, mice used as test subjects may all come from the same gene pool, potentially skewing results.

Dr Susanne Pors, who led the research, said "a bioengineered ovary would allow the growth and development of reseeded frozen-thawed early stage follicles in a tissue bed which is free of malignancies".

Doctors have developed an "artificial ovary" from human eggs and tissue so as to aid women to give birth after the treatment for cancer and different other therapies that can harm women's fertility.

The decellularised scaffold was made up of a mix of the proteins and collagens left behind.

The findings of the study were disclosed through a research paper released during an annual meeting held by the European Society of Human Reproduction and Embryology which provided more details about the way followed by the associated scientists to create the artificial ovaries. If the "scaffold" artificial ovary option works, it could restore a woman's fertility using their eggs and possibly donor tissue.

Follicles, unlike ovarian tissue cells, do not contain cancer, Pors said. What remained after the three day period was a "decellularized scaffold".


As a proof-of-concept, Pors said it could offer a new strategy in fertility preservation without risk of cancer reoccurrence.

He added that the new technique transplants only the eggs and surrounding cells of the follicle (seeded into a matrix) back into the uterus.

The Daily Telegraph reported that the "artificial ovary" was implanted into a mouse, and the process succeeded after several attempts.

The approach has been garnering praise from the scientific community, but more research is needed. They are thrust into premature menopause, and although the use of hormone replacement therapy and their own cryopreserved eggs allows some of these women to become pregnant, their natural hormones and natural fertility will not be renewed.

This is perhaps the only treatment for preserving fertility in women.

The technique will be of particular benefit to female cancer sufferers whose fertility is often destroyed by radio and chemotherapy, as well as patients with multiple sclerosis and certain blood disorders.

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