Immune therapy key to extending lung cancer patients' lives

Immune therapy key to extending lung cancer patients' lives

In another study, the combination of Bristol-Myers Squibb's Opdivo and Yervoy worked better than chemo alone for delaying the time until cancer worsened in advanced lung cancer patients whose tumors have many gene flaws, as almost half do, AP reported.

"Ive been treating lung cancer for 25 years now, and Ive never seen such a big paradigm shift as were seeing with immunotherapy", said Dr. Roy Herbst, chief of Medical Oncology at the Yale Cancer Center.

Due to the significant time delay when collecting complicated data, the statistics released by the NCC are for 2014. "We have patients on these immunotherapies alive more than eight years".

The Framework is the result of a four-year collaborative process involving cancer specialists and other health professionals, health service providers and consumers across Australia. The NCC believes that it is caused by over-exposure to second-hand smoking and cooking oil fumes. Worldwide, lung cancer causes 1.69 million deaths annually.

Recalling a patient with advanced lung cancer whose tumor disappeared and has not grown back after finishing treatment 24 months ago, Gomez said, "I'm now becoming much more optimistic that if we can really find a way to ideal this treatment and to really figure out who are the patients who do the best and why that we may be able to do something like get rid of lung cancer for at least some patients".

Other studies in lung cancer have involved another checkpoint inhibitor, nivolumab, or Opdivo (made by Bristol-Myers Squibb), which works in a similar way to pembrolizumab. It's a sign that checkpoint inhibitors like Keytruda, which unleash a patient's immune system to fight cancer, are on their way to becoming first-line therapies for cancer.

A separate study tested the immunotherapy drug nivolumab, on 21 patients about to have surgery for non-small-cell lung cancer
A separate study tested the immunotherapy drug nivolumab, on 21 patients about to have surgery for non-small-cell lung cancer

The immune therapy treatments worked for only about half of the patients in the study.

For non-squamous non-small cell lung cancer patients, median survival with chemotherapy alone is somewhere around 11 or 12 months, he said.

Immune-boosting drugs given in conjunction with chemotherapy significantly extended life for people with the most common type of lung cancer, according to clinical trials.

Gandhis study included 616 patients with advanced lung cancer, from medical centers in 16 countries.

After a median followup of 10.5 months, those in the immunotherapy group were half as likely to die.

The estimated survival after a year was 69 per cent in those taking the immunotherapy drugs compared to 49 per cent who only had chemotherapy.


Related Articles

  • ATMs run out of cash: What Arun Jaitley has to say

    ATMs run out of cash: What Arun Jaitley has to say

    Public sector bank executives also said there is a spurt in demand for cash to make payments for agricultural activities as well. People in Madhya Pradesh, Delhi, Bihar, Gujarat and Telangana too have reported problems in withdrawing money from ATMs.
    Sri Lanka joins Commonwealth alliance to fight against plastic pollution

    Sri Lanka joins Commonwealth alliance to fight against plastic pollution

    Global broadcasters Sky and National Geographic have teamed up to drive a global media campaign to reduce plastic litter in the ocean.
    Microsoft Corporation (MSFT) Try to Shakeup Active Momentum on New Compulsions

    Microsoft Corporation (MSFT) Try to Shakeup Active Momentum on New Compulsions

    Obermeyer Wood Inv Counsel Lllp holds 200,295 shares. 34,728 are held by Polaris Capital Management Limited Company. (NASDAQ:FB). Portolan Capital Management Ltd Liability Corporation stated it has 45,942 shares. (NYSE:GS) for 32,078 shares. (NASDAQ:CTWS).
  • Police hunt woman accused of killing her husband, then her look-alike

    Police hunt woman accused of killing her husband, then her look-alike

    Customs and Border Protection officials have her information and the license plate number for Hutchinson's stolen Acura sedan. The authorities after further investigations informed that Riess flew to Florida, befriended her twin and killed her.
    Syrian air defence shoots down missiles over Homs

    Syrian air defence shoots down missiles over Homs

    Asked about the missile attack, an Israeli military spokesman told Reuters, "We don't comment on such reports". Syrian news agency SANA stated that "Syrian air defense shot down missiles which violated airspace over Homs".
    'Night Court' actor Harry Anderson dies at 65

    'Night Court' actor Harry Anderson dies at 65

    Following Night Court , he starred on the sitcom Dave's World , which was based on the humor columnist Dave Barry. Night Court co-star Markie Post, who played Christine Sullivan, wrote, "I am devastated".
  • Apple Inc. (AAPL) -Trending stock

    Apple Inc. (AAPL) -Trending stock

    He reiterated his market perform rating on shares. (NASDAQ: AAPL ) has "Buy" rating given on Friday , November 3 by Bernstein. Technical Analysis of Apple Inc.: Technical indicators do not lead us to assume the stock will see more gains anytime soon.
    Ousting King Mark From Facebook Would Be Hard

    Ousting King Mark From Facebook Would Be Hard

    The stock was already getting stable after the investors digested the remarks from Zuckerberg following the Cambridge Analytica scandal .
    Armed robbery reported Monday morning in Moline

    Armed robbery reported Monday morning in Moline

    The 17-year-old said he had set up the deal on the social media platform Snapchat with two fellow Bryant High School students. Columbia police arrested Devon Busch and Trevion Travis after an attempted armed robbery in the 1400 block of Bass Avenue.
  • Bodies of all missing Thottapilly family members found

    Bodies of all missing Thottapilly family members found

    Still missing is the Thottapillys' son Siddhant, 12; search and rescue efforts are still underway to find the young boy. After seven hours of recovery efforts, the vehicle was partially removed from the river by a tow truck.
    Hiroshima: Man, 44, accused of stabbing woman who later died

    Hiroshima: Man, 44, accused of stabbing woman who later died

    A man in his 20s has been arrested on suspicion of murder over the Brixton attack and is now in custody. Post mortem examinations on the bodies of both the victims are expected in "due course", the Met said.
    Prosecutor wants Meek Mill's drug and gun convictions tossed

    Prosecutor wants Meek Mill's drug and gun convictions tossed

    TMZ reported that if the Philadelphia District Attorney office's wishes are granted, Mill's 2008 conviction would be thrown out. Freedom for Meek Mill would just be another sign the 76ers, who've aligned themselves with Mill's freedom, are on a roll.